Dynamics of Lateral Processes in Monolayers and Bilayers at Interfaces

该计划延续了一个成功的现有计划，进入有组织的，多分子表面活性剂分子组装的研究。化学组成，物理结构和组织这些组件的程度将被调查。该项目旨在测量合成磷脂双层的流动性作为磷脂结构和表面浓度的函数；表征胆固醇对膜流动性的影响，并进行可能导致胆固醇传感器的研究；研究了这些组合中的电子跳跃和质子扩散；并利用单层薄膜在电极表面开发手性选择性和门控特性。在分析和表面化学的一般领域，研究重点是研究界面上单层和双层的横向过程动力学。本研究旨在模拟生物膜系统的结构和功能。该项目继续进行一项重要计划，旨在开发研究固溶和空气-水界面模型膜系统的新方法。这项研究的结果不仅对我们对电化学和薄膜的理解很重要，而且对理解膜在生物系统中的作用也很重要。

The program continues a successful existing program into the study of organized, multimolecular assemblies of surfactant molecules. Chemical composition, physical structure and the extent of organization of these assemblies will be investigated. The project aims to measure the fluidity of synthetic phospholipid bilayers as a function of phospholipid structure and surface concentration; to characterize the effect of cholesterol on the membrane fluidity and studies that may lead to a cholesterol sensor; to investigate the electron hopping and proton diffusion in these assemblies; and to develop chiral selectivity and gating properties at electrode surfaces using monolayer films. %%% The research, in the general area of Analytical and Surface Chemistry, focuses on studies of the dynamics of lateral processes in monolayers and bilayers at interfaces. The research is intended to mimic the structures and functions of biological membrane systems. The project continues an important program aimed at developing new methods for the study of model membrane systems at solid-solution and air-water interfaces. The outcome of the research will be important not only in our understanding of electrochemistry and thin films, but will also have considerable importance in the understanding of membrane action in biological systems.