Grant for Exploratory Research: ESR Imaging Without DC Magnetic Field Gradients

探索性研究资助：无直流磁场梯度的 ESR 成像

• 批准号: 9108579
• 负责人: Joseph Hornak
• 金额: $ 4.44万
• 依托单位: Rochester Institute of Tech
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-05-15 至 1992-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9108579&HistoricalAwards=false
• 关键词: Grant; Exploratory; Research; ESR; Imaging

This research, supported by the Analytical and Surface Chemistry Program in the Chemistry Division, seeks to design and build novel instrumentation for Electron Spin Resonance (ESR) imaging. Programmed phasing of radio frequency signal inputs rather than magnetic field gradients will be employed. Lower frequencies than are commonly employed for ESR spectrometry will also be employed, reducing the problems of sample heating. If successful, this Grant for Exploratory Research should lead to radically different ESR imaging instrumentation than would otherwise be available. %%% Magnetic Resonance Imaging has profoundly improved diagnostic medicine. Electron Spin Resonance imaging has not had the impact of Nuclear Magnetic Resonance, due to instrumental as well as fundamental difficulties in generating signals. In this research, supported by the Analytical and Surface Chemistry Program in the Chemistry Division, a novel means of generating electron spin images which may overcome several of the previously identified problems will be built and studied. This Grant for Exploratory Research is considered to be high risk, but the reward (the ability to routinely image free radicals in situ without roasting the object studied) makes the risk worthwhile.

这项研究得到了分析和表面的支持， 化学系的化学课程，旨在设计 并为电子自旋共振技术 (ESR)显像 射频信号的程控定相 将采用输入而不是磁场梯度。 低于ESR常用的频率 还将采用光谱测定法，减少 样品加热 如果成功的话，这项探索性的补助金 研究应该导致完全不同的ESR成像 比其他方式更好的工具。 %%% 磁共振成像极大地改善了诊断 药 电子自旋共振成像还没有 核磁共振的影响，由于仪器作为 以及产生信号的基本困难。 在 这项研究由分析和表面支持， 化学系的化学课程，一种新颖的方法， 产生电子自旋图像，其可以克服以下几个问题： 将建立和研究先前确定的问题。 这项探索性研究补助金被认为是高 风险，但回报（能够定期图像免费 自由基原位不焙烧研究对象）， 值得冒险。