Separations of Macromolecules of Environmental Interest by Flow Field-Flow Fractionation

该职业发展奖将使Wells博士获得场流分馏分析分离领域的新技能。场流分馏能够分辨和表征大范围的大分子、胶体和颗粒材料。这个项目的重点是用这些方法分离对环境有重要意义的大分子。场流分馏将用于确定溶解有机大分子的分子量和多分散性，并将有助于研究分馏大分子与人为环境污染物之间的相互作用。这对环境具有重大意义。这项活动的目标是提高在场流分馏的理论和应用方面的能力。这项技术将用于实验，旨在了解自然发生的大分子，如腐植酸和黄腐酸及其成分的化学。将着重介绍这些大分子的分子量和多分散性的测定以及半制备回收。该职业进步奖将支持扩大威尔斯博士研究职业潜力的活动。该奖项将提供获得新的技能，将丰富她的研究活动的领域。这次活动将补充她之前在政府和行业的专业活动。

This Career Advancement Award will allow Dr. Wells to acquire new skills in the analytical separations area of field flow fractionation. Field flow fractionation is capable of resolving and characterizing a broad range of macromolecular, colloidal, and particulate materials. This project focuses on the separation of large molecules of environmental importance by these methods. Field flow fractionation will be used to determine the molecular weight and polydispersity of dissolved organic macromolecules and will be useful in studies of the interactions between fractionated macromolecules and anthropogenic environmental contaminants. This is of substantial environmental significance. The objectives of this activity are to establish greater competence in the theory and application of field flow fractionation. This technique will be used in experiments aimed at understanding the chemistry of naturally-occurring macromolecules such as humic and fulvic acids and their constituents. Determinations of molecular weight and polydispersity, and semi-preparative recovery of these macromolecules will be emphasized. %%% This Career Advancement Award will support activities that will expand Dr. Wells' research career potential. The award will provide for the acquisiton of new skills in areas that will enrich her research activities. This activity will complement her previous professional activities in government and industry.