Synthesis and Reactivity of Complexes of Transition Metals in Negative Oxidation States

负氧化态过渡金属配合物的合成及反应活性

• 批准号: 9113808
• 负责人: N. John Cooper
• 金额: $ 32.4万
• 依托单位: University of Pittsburgh
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-01 至 1995-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9113808&HistoricalAwards=false
• 关键词: Synthesis; Reactivity; Complexes; Transition; Metals

Two broad topics will be investigated - the synthesis of highly reduced carbene complexes of transition metals in negative oxidation states, and pericyclic reactions of reductively activated aromatic ligands. The principal objective of the studies is to answer three broad questions: 1) What range of pi-acceptor ligands is capable of stabilizing complexes of metals in negative oxidation states?, 2) How wide is the range of accessible complexes for those classes of ligands which do prove to be capable of stabilizing negative oxidation states?, and 3) Will pi-back-donation of electron density from highly reduced metal centers to the (typically unsaturated) pi-acceptor ligands activate the ligands towards electrophiles, coupling reactions, or other unprecedented reactivity modes? An important secondary objective is the development of new reactions with potential applications in organic synthesis. %%% In this project in the Inorganic, Bioinorganic, and Organo- metallic Program of the Chemistry Division, Dr. N. John Cooper of the University of Pittsburgh will synthesize and study the reactivity of complexes containing transition metals in negative oxidation states. These very unusual and highly reactive compounds may have applications in organic synthesis.

将研究两个广泛的主题-高度综合 负极性过渡金属的还原卡宾配合物 氧化态和还原性的周环反应 活性芳族配体。 的主要目标 研究是为了回答三个广泛的问题：1）什么范围的 π-受体配体能够稳定以下的络合物： 负氧化态的金属？2)范围有多宽 对于那些配体类型， 证明能够稳定负氧化态， 以及3）将π-反馈电子密度从高 还原金属中心（通常为不饱和） π-受体配体活化配体朝向亲电体， 耦合反应，或其他前所未有的反应模式？ 一个重要的次要目标是开发新的 在有机合成中具有潜在应用的反应。 %%% 在这个项目中，无机，生物无机和有机- 化学部金属计划，N。约翰·库珀 匹兹堡大学将综合和研究 含过渡金属的络合物的反应性 负氧化态 这些非常不寻常和高度 反应性化合物可用于有机合成。