Understanding the mechanisms that inhibit and promote biofilm expansion

点击翻译按钮获取中文摘要

Yeasts have been used for biotechnology throughout recorded history. They are important human pathogens, and major experimental models of eukaryotic cells. Although yeasts are some of the most studied organisms in biology, their modes of colony biofilm formation are not fully understood. Methods to investigate the environmental and genetic processes that drive colony biofilm formation will be developed in this proposed project. They will provide a deeper understanding of the mechanisms that inhibit and promote biofilm formation, and colonial morphology in the different modes of growth of Saccharomyces cerevisiae, with implications for this and other biofilm-forming yeasts of biotechnological or medical importance.