Understanding the mechanisms that inhibit and promote biofilm expansion

酵母在有记载的历史中一直用于生物技术。它们是重要的人类病原体，也是真核细胞的主要实验模型。虽然酵母是生物学中研究最多的生物体，但它们的菌落生物膜形成模式尚未完全了解。在这个项目中，我们将研究驱动菌落生物膜形成的环境和遗传过程的方法。他们将提供抑制和促进生物膜形成的机制，并在酿酒酵母的不同生长模式的菌落形态，与此和其他生物膜形成酵母的生物技术或医学重要性的影响，有更深入的了解。

Yeasts have been used for biotechnology throughout recorded history. They are important human pathogens, and major experimental models of eukaryotic cells. Although yeasts are some of the most studied organisms in biology, their modes of colony biofilm formation are not fully understood. Methods to investigate the environmental and genetic processes that drive colony biofilm formation will be developed in this proposed project. They will provide a deeper understanding of the mechanisms that inhibit and promote biofilm formation, and colonial morphology in the different modes of growth of Saccharomyces cerevisiae, with implications for this and other biofilm-forming yeasts of biotechnological or medical importance.