US-Poland Research on Chemistry of Core-Modified Porphryins

加州大学戴维斯分校的艾伦·L·巴尔奇博士和波兰弗罗茨瓦夫大学化学研究所的莱科斯瓦夫·拉托斯-格拉津斯基博士之间的这一美国-波兰研究项目的目标是是探索核心修饰的卟啉的合成和配位性质--一个或多个吡咯氮基被改变的卟啉，特别是通过用不同的杂原子取代的方法。研究人员预计，这些配体将稳定金属离子在低氧化态和平面，而不是四面体几何结构。我们将考察金属离子在这些不寻常的环境中的反应性。他们将继续研究硫代卟啉的配位性质，特别是它们的(形式)Ni(I)和Pd(I)配合物。这些结果有望提高我们对矿物生物化学某些方面的理解，并可能产生对有机分子的烷基化或氧化具有良好催化作用的络合物。这个化学项目通过使美国和东欧的顶尖专家能够将互补的人才结合在一起，并在相互感兴趣和能力很强的领域汇集资源，从而实现了促进科学知识的计划目标。

The objective of this US-Poland research project between Dr. Alan L. Balch of the University of California-Davis and Dr. Lechoslaw Latos-Grazynski of the Institute of Chemistry, University of Wroclaw, Poland, is to explore the synthesis and coordination properties of core-modified porphyrins -- porphyrins which one or more of the pyrrole nitrogens has been altered, particularly by replacement with a different heteroatom. The researchers anticipate that these ligands will stabilize metal ions in low oxidation states and in planar, rather than tetrahedral geometry. The reactivity of the metal ions in these unusual environments will be examined. They will continue their studies of the coordination properties of monothiaporphyrins, particularly their (formal) Ni(I) and Pd(I) complexes. Results are expected to improve our understanding of certain aspects of metallobiochemistry and may yield complexes that are good catalysts for alkylation or oxidation of organic molecules. This project in chemistry fulfills the program objective of advancing scientific knowledge by enabling leading experts in the United States and Eastern Europe to combine complementary talents and pool resources in areas of strong mutual interest and competence.