Bimetallic Cooperativity in Catalysis

该奖项在无机、生物无机和有机金属项目中继续支持路易斯安那州立大学巴吞鲁日分校化学系的乔治·G·斯坦利博士在催化方面的研究。制备了双核四(叔膦)配体的双金属铑配合物，并用于氢甲酰化反应的选择性催化。如果Rh中心被长的配体链分开，催化剂就会失去活性，这表明双金属的协作性是影响催化剂活性的一个重要因素。斯坦利将研究这一反应的机制和动力学，以了解双金属协作性步骤的确切性质。此外，还将测试含其他金属和混合金属的络合物的有效性，并探索该体系对不对称催化反应的适用性。氢甲酰化是将烯烃转化为醛的化学过程，使用氢气和一氧化碳作为其他反应物。该工艺被广泛用于商业生产醛和醇。斯坦利将研究用于该反应的新催化剂的反应，目的是了解反应机理的细节，并测试有助于生产特定产品的催化剂。

This award in the Inorganic, Bioinorganic, and Organometallic Program provides continued support for research on catalysis by Dr. George G. Stanley of the Chemistry Department, Louisiana State University at Baton Rouge. Bimetallic rhodium complexes of binucleating linear tetra(tertiaryphosphine) ligands have been prepared and used as selective catalysts for hydroformylation reactions. The catalysts become inactive if the rhodium centers are separated by long ligand chains, suggesting that bimetallic cooperativity is an important factor in their activity. Stanley will study the mechanism and kinetics of this reaction in order to understand the exact nature of the bimetallic cooperativity step. In addition, the effectiveness of complexes containing other metals and mixed metals will be tested and the suitability of the system for asymmetric catalytic reactions will be explored. &&Hydroformylation is the chemical process of converting alkenes into aldehydes, using hydrogen gas and carbon monoxide as the other reactants. The process is widely used commercially to produce aldehydes as well as alcohols. Stanley will study the reactions of new catalyts for this reaction with the goals of understanding the details of the reaction mechanism and of testing catalysts which can favor the production of specific products.