Long and Medium-Term Research: Cellular Analysis of Cell Cycle Regulatory Phosphoproteins and Cytoskeletal Proteins in Developmental Mutants of Nicotiana and Arabidopsis

长期和中期研究：细胞的细胞分析 细胞周期调节磷蛋白和细胞骨架蛋白 烟草和拟南芥的发育突变体 该奖项是根据长期和中期研究， 外国卓越中心计划，使美国 科学家和工程师将进行三到十二个月的 在国外被证明卓越的研究中心进行研究。 的 该计划的奖项提供了联合研究的机会， 利用独特或互补的设施、专门知识和 国外的实验条件。 该奖项将支持为期十二个月的博士后研究访问 海蒂·S博士与杨博士合作。Traas在研究所 法国凡尔赛的National de la Recherche Agronomique Feiler博士计划对几种烟草属和拟南芥属植物进行鉴定， 发育突变体，在细胞周期调节中受到干扰 和分割平面对准。 利用原位细胞生物学 技术，她将研究表达和亚细胞 定位一组高度保守的磷蛋白， 参与细胞周期控制的细胞骨架蛋白。 是 我推测这些蛋白质的一个子集将作为标记物， 在正常和异常细胞周期控制之间划定界限， 这样的比较将有助于确定细胞的贡献 对植物生长发育的周期调控。 分析了细胞和 cdc 2和MPM-2的亚细胞定位模式 磷蛋白调节剂和潜在的细胞骨架原位靶点 将更好地定义它们的交互式体内功能。 实验 如这些将需要最终了解细胞周期 当它发生在工厂。 该奖项的建议提供资金，以支付国际 旅行和12个月的津贴

Long and Medium-Term Research: Cellular Analysis of Cell Cycle Regulatory Phosphoproteins and Cytoskeletal Proteins in Developmental Mutants of Nicotiana and Arabidopsis This award is under the Long and Medium-Term Research at Foreign Centers of Excellence Program, which enables U.S. scientists and engineers to conduct three to twelve months of research abroad at research centers of proven excellence. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a twelve-month postdoctoral research visit by Dr. Heidi S. Feiler to work with Dr. Jan A. Traas at the Institut National de la Recherche Agronomique in Versailles, France. Dr. Feiler plans to characterize several Nicotiana and Arabidopsis developmental mutants, which are perturbed in cell cycle regulation and division plane alignment. Using in situ cell biology techniques, she will study the expression and subcellular localization of a set of highly conserved phosphoproteins and cytoskeletal proteins implicated in cell cycle control. It is presumed that a subset of these proteins will act as markers delineating between normal and aberrant cell cycle control and that comparisons such as these will help identify the contribution of cell cycle regulation to plant development. The analysis of cellular and subcellular localization patterns of the cdc2 and MPM-2 phosphoprotein regulators and potential cytoskeletal targets in situ will better define their interactive, in vivo functions. Experiments such as these will be required to ultimately understand cell cycle regulation as it occurs within the plant. The award recommendation provides funds to cover international travel and a stipend for twelve months.