U.S.-Argentina Cooperative Science Program: Characterizationof Genes Involved in Sex Determination and Sex Reversal in Akodon (Cricetidae) Rodents

美国-阿根廷合作科学计划：仓鼠科啮齿动物性别决定和性别逆转相关基因的表征

• 批准号: 9202155
• 负责人: Yun-Fai Lau
• 金额: --
• 依托单位: University of California-San Francisco
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-01 至 1995-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9202155&HistoricalAwards=false
• 关键词: U.S.; Argentina; Cooperative; Science; Program

This award from the U.S.- Argentina Cooperative Science Program supports research in biology to be conducted by Dr. Yun-Fai C. Lau of the University of California, San Francisco and Dr. Nestor O. Bianchi of IMBICE, La Plata, Argentina. The project focuses on the study of sex determination in Akodon rodents. The project takes advantage of the fact that several species of rodents from the Genus Akodon in South America possess some peculiar sex determination mechanisms in which there is a disproportion of females harboring both X and Y chromosomes in their karyotypes. These rodents will be studied to investigate the mammalian sex determination process and to test the involvements of several recently isolated candidate genes for the testis determining Y (Tdy) locus on the Y chromosome. The award will support a collaborative effort by two recognized experts in the field of mammalian sex determination.

美国的这个奖-阿根廷合作社 科学计划支持生物学研究， 由C.尹辉博士主持。的刘 加州大学，旧金山弗朗西斯科和博士。 内斯特·O.拉普拉塔IMBICE的比安奇， Argentina. 该项目重点研究 Akodon啮齿动物的性别决定。 该项目利用了这样一个事实， 几种啮齿类动物 南美洲的阿科顿拥有一些特殊的性别 确定机制，其中有一个 女性同时携带X和Y染色体比例失调 染色体在他们的核型。 这些啮齿动物 将被用来研究哺乳动物 性别决定过程，并测试 几个最近被隔离的 睾丸决定Y染色体的候选基因 (Tdy)在Y染色体上。 该奖项 将支持由两个 哺乳动物领域公认的专家 性别决定