Long and Medium-Term Research: Solvent Design for Separation of Biomolecules Using Supercritical Fluids

中长期研究：使用超临界流体分离生物分子的溶剂设计该奖项是根据外国卓越中心长期和中期研究计划颁发的，这使得美国科学家和工程师能够在国外被证明是卓越的研究中心进行为期三到十二个月的研究。该项目的奖项提供了联合研究的机会，并提供了使用国外独特或互补的设施、专业知识和实验条件的机会。这一奖项将支持大卫·托马斯科博士在新南威尔士大学与尼尔·R·福斯特博士合作进行为期11个月的博士后研究访问。以超临界流体为基础，可以开发出适用于食品、化妆品和制药行业的分离工具。这些领域对毒性和纯度的严格要求要求高度具体的设计，这些设计必须以准确的实验数据为基础。脂肪酸、甘油三酯及其混合物的溶解度将在纯和共溶剂改性的超临界流体中进行测量，以帮助为这一要求苛刻的应用进行分离设计。这一应用的独特性展示了一种新的分离技术，适用于一个由美国传统技术主导的领域。奖励建议提供了国际旅费、11个月津贴和受抚养人津贴的经费。

Long and Medium-Term Research: Solvent Design for Separation of Biomolecules Using Supercritical Fluids This award is under the Long and Medium-Term Research at Foreign Centers of Excellence Program, which enables U.S. scientists and engineers to conduct three to twelve months of research abroad at research centers of proven excellence. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support an eleven-month postdoctoral research visit by Dr. David Tomasko to work with Dr. Neil R. Foster at the University of New South Wales. Separation tools suitable for use in the food, cosmetics, and pharmaceutical industries can be developed using supercritical fluids as a basis. The stringent toxicity and purity requirements in these fields require highly specific designs which must be based on exact experimental data. Solubilities of fatty acids, triglycerides, and their mixtures will be measured in pure and cosolvent modified SCF's to aid the separation design for this demanding application. The uniqueness of this application demonstrates a novel separation technique applicable in an area that is dominated by conventional technology in the United States. The award recommendation provides funds to cover international travel and a stipend for eleven months and a dependent allowance.