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Targeted therapy of meningiomas: establishing the therapeutic role and molecular mechanisms of epigenetic modification in clinically aggressive meningiomas in vivo and in vitro

Targeted therapy of meningiomas: establishing the therapeutic role and molecular mechanisms of epigenetic modification in clinically aggressive meningiomas in vivo and in vitro
脑膜瘤的靶向治疗：建立表观遗传修饰在临床侵袭性脑膜瘤体内和体外的治疗作用和分子机制
批准号：
437192
负责人：
Wang Justin Z
金额：
$10.93万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-11-01 至 2023-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=437192&lang=en
关键词：
Brain Tumour Epigenetics Genetics Meningioma Methylation Molecular Biology Xenograft

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中文摘要
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英文摘要
Meningiomas are most common brain tumour in adults but are severely understudied compared to other tumours. Most meningiomas are benign and can be successfully treated with surgery. However, there are a significant cohort of meningiomas (20-30%) that are
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会议论文
Establishing the utility of plasma-based liquid biopsies in meningiomas using cell-free methylated DNA immunoprecipitation with deep sequencing
  • 批准号：
    441432
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $20.03万
  • 财政年份：
    2020
  • 负责人：
    Wang Justin Z
  • 依托单位：
    University Health Network (Toronto)
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