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Establishing the utility of plasma-based liquid biopsies in meningiomas using cell-free methylated DNA immunoprecipitation with deep sequencing

Establishing the utility of plasma-based liquid biopsies in meningiomas using cell-free methylated DNA immunoprecipitation with deep sequencing
使用无细胞甲基化 DNA 免疫沉淀和深度测序建立基于血浆的液体活检在脑膜瘤中的实用性
批准号：
441432
负责人：
Wang Justin Z
金额：
$20.03万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-12-01 至 2025-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=441432&lang=en
关键词：
Epigenetics Liquid Biopsy Meningioma Methylation Neurosurgery Plasma

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中文摘要
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英文摘要
Meningiomas are the most common brain tumour in adults and the majority are benign. However, there are a subset of clinically aggressive meningiomas that recur repeatedly despite maximal standard of care with surgery and adjuvant radiation. Without a samp
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Targeted therapy of meningiomas: establishing the therapeutic role and molecular mechanisms of epigenetic modification in clinically aggressive meningiomas in vivo and in vitro
  • 批准号：
    437192
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2020
  • 负责人：
    Wang Justin Z
  • 依托单位：
    University of Toronto
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