Grant for Exploratory Research: A Novel Source of Natural Products from Plant Associated Microbes

探索性研究资助：植物相关微生物天然产物的新来源

• 批准号: 9206803
• 负责人: Gary Strobel
• 金额: $ 5万
• 依托单位: Montana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-02-15 至 1994-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9206803&HistoricalAwards=false
• 关键词: Grant; Exploratory; Research; Novel; Source

The focus of this research is to discover if endophytic and pathogenic fungi isolated from the inner bark (phloem, cambium), leaves and roots of Taxus brevifolia and other Taxus sp. have acquired the ability to produce interesting natural products, such as taxol, which are thought to be unique to the tree. The project could provide a source of important natural products that are in critically short supply. %%% With this Small Grant for Exploratory Research (SGER), the Synthetic Organic Program is supporting the research of Dr. Gary A., Strobel of the Plant Pathology Department at Montana State University. The fundamental hypothesis to be tested in this project is whether microbes (fungi) living in close association with higher plants aquire the ability to produce specific compounds that appear to be unique to the plant genus.

这项研究的重点是发现，如果内生和 从内树皮（韧皮部， 形成层）、短叶红豆杉和其它红豆杉属植物的叶和根 已经获得了产生有趣的自然的能力， 产品，如紫杉醇，这被认为是独特的， 树该项目可以提供重要的自然资源， 严重短缺的产品。 %%% 有了这个探索性研究的小补助金（SGER）， 合成有机计划是支持博士的研究。 加里A.，蒙大拿大学植物病理学系的斯特罗贝尔说， 州立大学。 要检验的基本假设是 这个项目是微生物（真菌）是否生活在接近 与高等植物的联系获得了生产的能力 似乎是植物属所特有的特定化合物。