Tracing the Cellular and Molecular Origins of Mouse and Human Medulloblastoma

追踪小鼠和人类髓母细胞瘤的细胞和分子起源

• 批准号: 444802
• 负责人: Dirks Peter B
• 金额: $ 69.66万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2026-04-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444802&lang=en
• 关键词: Cancer Stem Cells; Medulloblastoma; Stem Cells

Medulloblastoma is a common childhood malignant brain tumour that has a 70% 5 year survival but only with therapy that is toxic to the developing nervous system and with a significant risk of secondary cancers. My lab discovered that medulloblastoma growt

髓母细胞瘤是一种常见的儿童恶性脑肿瘤，5年生存率为70%，但只有在对发育中的神经系统有毒的治疗下，才有继发性癌症的显著风险。我的实验室发现成神经管细胞瘤