Characterizing the role of Wnt signaling in human medulloblastoma stem cells

表征 Wnt 信号在人髓母细胞瘤干细胞中的作用

• 批准号: 224327
• 负责人: Manoranjan Branavan
• 金额: $ 1.27万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-02-01 至 2012-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=224327&lang=en
• 关键词: Cancer Stem Cells; Cell Signaling (Wnt; Developmental Neurobiology; Epigenetics; Human Brain Tumours; Human-Mouse Xenografts; Molecular Biology; Neural Stem Cells; Oncogenes; Shh); Signal Transduction

Medulloblastomas are the most common type of brain tumours in children. Recent research has categorized these tumours into four subtypes (A, B, C, D) based on the effects of specific proteins. Subtype A is characterized by the involvement of Wnt proteins.

髓母细胞瘤是儿童脑肿瘤中最常见的类型。最近的研究根据特定蛋白质的作用将这些肿瘤分为四种亚型（A、B、C、D）。亚型A的特征在于Wnt蛋白的参与。