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Determining the molecular mechanisms of titin's role in active force production in striated muscles

Determining the molecular mechanisms of titin's role in active force production in striated muscles
确定肌动蛋白在横纹肌主动力产生中的作用的分子机制
批准号:
443890
负责人:
Herzog Walter
金额:
$72.78万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01

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中文摘要
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英文摘要
Textbooks of muscle physiology state that muscle contraction and force production are entirely accounted for by two proteins, actin and myosin. This actin and myosin-based theory was developed in the mid-1950 by Nobel Prize winner Andrew Huxley, and it ha
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Mechanistic Exploration of the Factors Underlying Musculoskeletal Degeneration in a Rat Model of Diet-Induced Obesity: Exercise and Diet Interventions
  • 批准号:
    461441
  • 项目类别:
    Operating Grants
  • 资助金额:
    $96.97万
  • 财政年份:
    2022
  • 负责人:
    Herzog Walter
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    332853
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2014
  • 负责人:
    Herzog Walter
  • 依托单位:
Cellular and Molecular Biomechanics of the Musculoskeletal System
  • 批准号:
    312403
  • 项目类别:
    Operating Grants
  • 资助金额:
    $176.36万
  • 财政年份:
    2014
  • 负责人:
    Herzog Walter
  • 依托单位:
The functional role of titin in muscle contraction
  • 批准号:
    280382
  • 项目类别:
    Operating Grants
  • 资助金额:
    $39.34万
  • 财政年份:
    2013
  • 负责人:
    Herzog Walter
  • 依托单位:
海外基金