Chondrocyte mechanics and biology in the intact joint: towards an understanding of osteoarthritis development in vivo

完整关节中的软骨细胞力学和生物学：了解体内骨关节炎的发展

• 批准号: 211413
• 负责人: Herzog Walter
• 金额: $ 38.5万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2015-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=211413&lang=en
• 关键词: Biomechanics; Cell Signalling; Chondrocytes; Joint Degeneration; Ostearthritis

Osteoarthritis (OA) is a debilitating disease of the joint. It affects approximately half of Canada's population aged sixty and older. It is associated with pain, joint stiffness, loss of muscle mass, impaired mobility, and it harms the quality of life of

骨关节炎（OA）是一种使关节衰弱的疾病。它影响了大约一半的加拿大60岁及以上的人口。它与疼痛、关节僵硬、肌肉量减少、活动能力受损有关，并损害患者的生活质量