Characterization of Protein Structure and Dynamics by NMR and Fluorescence Spectroscopies

该奖项是作为亚瑟·帕尔默博士博士后研究奖学金的启动资助增量。帕尔默博士将应用核磁共振和荧光光谱来确定分子化学的结构和动态方面。要研究的系统分为配体结合核糖核酸酶动力学的情况，蛋白质识别核酸的动力学方面，以及膜受体蛋白的结构方面。这项研究将促进对生物感兴趣的大分子如何移动以及它们如何与小分子相互作用的认识。这一领域的进展可以使人们更好地了解新陈代谢和代谢紊乱。

This award is made as the starter grant increment of Dr Arthur Palmer's postdoctoral research fellowship. Dr Palmer will apply NMR and fluorescence spectroscopies to the determination of structural and dynamic aspects ofmaromolecular chemistry. The systems to be studied fall into the categories of cases of ligand binding on the dynamics of ribonucleases, dynamic aspects of nucleic acid recognition by proteins, and structural aspects of membrane receptor proteins. %%% This research will advance the knowledge of how large molecules of biological interest move and how they interact with smaller molecules. Advances in this area can lead to a much better understanding of metabolism and metabolic disorders.