U.S.-Malaysia Cooperative Research: Bloom Dynamics and Physiology of the Toxic Red Tide Dinoflagellate Pyrodinium Bahamensa from Malaysia.

9224474安德森这项建议要求拨款，以允许马萨诸塞州伍兹霍尔波士顿大学海洋计划的博士生Gires Usup先生在伍兹霍尔海洋研究所唐纳德·M·安德森博士的指导下，在马来西亚进行为期24个月的关于有毒赤潮甲藻的水华动态和生理的论文改进研究。马来西亚沙巴州西海岸不断爆发有毒赤潮，已在该地区造成严重的公共卫生和经济问题。目前正在对来自沙巴州的一株分离物进行实验室培养的生理和毒性研究。本研究是沙巴州西海岸赤潮暴发动态研究的野外部分。采样巡航和监测计划将被用来定量描述这种有毒甲藻的时空分布、其种群的运动以及在水华发育期间发生的生物事件。还将对水华发生、水柱物理特征和气象条件之间的关系进行定量分析。有害或有害的藻类水华在世界许多沿海地区变得越来越普遍。当致病甲藻是一种有毒物种时，悬浮摄食的双壳类会将强大的神经毒素集中在它们的组织中。食用这些贝类会导致麻痹性贝类中毒，这可能会对人类，特别是儿童造成致命的伤害。安德森博士是研究赤潮甲藻的公认权威。Usup先生从沙巴校区马来西亚科邦桑大学海洋科学系讲师的职位上休假，也有这一领域的研究出版物。诺哈迪·伊斯梅尔先生将与Usup先生在马来西亚经济大学进行这些研究，他将在本研究中进行合作。该项目与东亚和太平洋计划的目标相关，该计划鼓励在东南亚等美国和外国调查人员互动有限的地区开展活动。***

9224474 Anderson This proposal requests funds to permit dissertation improvement research, in Malaysia, by Mr. Gires Usup, a Ph.D. student in the Boston University Marine Program, Woods Hole, MA, under the direction of Dr. Donald M. Anderson, Woods Hole Oceanographic Institution, within a 24-month period, on the bloom dynamics and physiology of the toxic red tide dinoflagellate Pyrodinium bahamensa. Recurring outbreaks of toxic red tides on the west coast of Sabah, Malaysia, have caused serious public health and economic problems in that region. Physiological and toxicity studies are currently underway on a laboratory culture of an isolate from Sabah. The present study is the field component of the dissertation project aimed at understanding the bloom dynamics of red tide outbreaks on the west coast of Sabah. Sampling cruises and monitoring programs will be used to quantitatively characterize the spatial and temporal distribution of this toxic dinoflagellate, the movement of its populations, and the biological events that take place during bloom development. The relationship between bloom occurrence, the physical characteristics of the water column, and meteorological conditions also will be quantitatively analyzed. Harmful or noxious algal blooms are becoming increasingly common in many coastal regions of the world. When the causative dinoflagellate is a toxic species, suspension-feeding bivalves concentrate the potent neurotoxins in their tissues. Consumption of these shellfish leads to paralytic shellfish poisoning which can be fatal to human beings, especially, children. Dr. Anderson is a recognized authority on red tide dinoflagellates. Mr. Usup, on leave from his position as Lecturer, Marine Sciences Department, University Kebangsaan Malaysia, Sabah Campus, also has research publications in this field. Mr. Norhadi Ismail, a co-author with Mr. Usup in these studies at Universiti Kebangsaan Malaysia, will collaborate in the present research. Th is project is relevant to the objectives of the East Asia and Pacific Program which encourages proposals for activities in regions such as Southeast Asia where interactions between U.S. and foreign investigators have been limited. ***