Grant for Exploratory Research: Specifically Functionalized Fulleroids: Synthesis of Interesting Spheroidal Molecules

本研究的重点是合成和表征能够与逆转录病毒逆转录酶(RT)和人类免疫缺陷病毒蛋白水解酶(HIVP)活性部位结合的功能化富勒类化合物。%有了这笔小额的探索性研究补助金(SGER)，合成有机计划正在支持加州大学圣巴巴拉分校聚合物和有机固体研究所的Fred Wudl博士的研究。研究的重点是合成新型功能化的中空球形分子Fulleroid，它有可能成为逆转录病毒特异性的生物活性分子。

The focus of this research is the synthesis and characterization of functionalized fulleroids that have the potential to bind to the active site of retroviral reverse transcriptases (RT) as well as the HIV protease (HIVP). %%% With this Small Grant for Exploratory Research (SGER), the Synthetic Organic Program is supporting the research of Dr. Fred Wudl of the Institute for Polymers and Organic Solids at the University of California, Santa Barbara. The focus of the research is the synthesis of novel functionalized hollow spheroidal molecules, fulleroids, that have the potential to be retrovirus-specific, biologically active molecules.