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Assessing the mechanisms behind, and human relevance of, an observed adipocyte-induced partial mesenchymal-to-epithelilal transition in triple negative breast cancer cells

Assessing the mechanisms behind, and human relevance of, an observed adipocyte-induced partial mesenchymal-to-epithelilal transition in triple negative breast cancer cells
评估三阴性乳腺癌细胞中观察到的脂肪细胞诱导的部分间质到上皮转变背后的机制和人类相关性
批准号：
486325
负责人：
Kelly Grant R
金额：
$1.27万
依托单位：
Memorial University of Newfoundland
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-12-01 至 2023-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486325&lang=en
关键词：
3d Cell Culture Adipocytes Adipokines Breast Cancer Extracellular Matrix Immunohistochemistry Mesenchymal-To-Epithelial Transition Metastasis Patient-Derived Xenograft Tumour Microenvironment

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Cancer cells which migrate from one place to another throughout the body, called metastatic cancer cells, are one of the major causes of death in cancer, especially breast cancer. To metastasize, cancer cells must first change from their initial rounded e
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