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Investigating the role of the T4 secretion system in the pathogenesis of Crohn's disease-associated bacteria

Investigating the role of the T4 secretion system in the pathogenesis of Crohn's disease-associated bacteria
研究 T4 分泌系统在克罗恩病相关细菌发病机制中的作用
批准号：
486606
负责人：
Asrar Tahreem
金额：
$1.27万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-12-01 至 2023-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486606&lang=en
关键词：
Antibiotic Resistance Bacterial Genomics Bacterial Pathogenesis Clinical Microbiology Crohn’S Disease Host-Pathogen Interactions Immunology Irritable Bowel Disease Microbiome T4 Secretion System

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Crohn's disease (CD) is caused by a dysregulated immune response to the microbiome. Adherent-invasive Escherichia coli (AIEC) strains are known to drive gut inflammation, yet the underlying mechanisms are unknown. We recently identified a role for the typ
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