Chemical and Mechanical Investigations of Boron Hydride Cluster Molecules

9305922 Gaines该项目由无机，生物无机和有机化学部门支持，将继续研究硼氢化物簇分子及其阴离子的基础化学。 具体目标是阐明1）骨架重排，2）簇烷基化，3）簇生长反应和4）导致氮基团衍生物的反应的机制。 这些研究将利用区域特异性同位素标记策略，这将需要开发一些化合物的新合成路线，并应用多核NMR技术。 这项研究关注的是被称为硼氢化物的化合物家族的某些成员的化学反应模式。 这项研究的结果可能最终导致化学合成的新试剂，高性能材料的新途径，以及中子捕获癌症治疗的更好试剂。 ***

9305922 Gaines This project, supported by the Inorganic, Bioinorganic and Organometallic Chemistry Division, will continue studies on the fundamental chemistry of boron hydride cluster molecules and their anions. Specific objectives are the elucidation of mechanisms of 1) skeletal rearrangements, 2) cluster alkylations, 3) cluster growth reactions, and 4) reactions leading to nitrogen group derivatives. These studies will utilize regiospecific isotopic labeling strategies, which will require the development of new synthetic routes to some compounds, and application of multinuclear NMR techniques. %%% This research is concerned with the chemical reactivity patterns of certain members of the family of compounds known as boron hydrides. The results of this research may ultimately lead to new reagents for chemical synthesis, new routes to high performance materials, and better agents for neutron capture cancer therapy. ***