Intercellular Communication of Bovine Luteal Cells: Role of Cyclic AMP

这是一个职业发展奖。 本研究的目的 研究环磷酸腺苷（cAMP）在调节 细胞内通讯在生长、分化和 黄体退化。 近期目标是研究 (1)接触依赖性细胞间通讯的个体发生 黄体细胞类型，和（2）CAMP的调节剂（例如， 促黄体生成素，毛喉素）对细胞内浓度的影响 CAMP和接触依赖性细胞间通讯在选择性 黄体细胞在黄体生长、分化和退化过程中。 %%% 这是一个职业发展奖，这是一个研究 国家科学院为妇女提供的机会 基金会 获奖者的主要研究兴趣是 调节家畜黄体功能， 着重于黄体形成过程中黄体细胞之间的相互作用， 生长发育和退化 这是一个重要的问题 在生殖生理学上。 该奖项将有助于 促进获奖者的科学事业以及基本的 了解家畜的生殖生物学。

This is a ROW Career Advancement Award. The goal of this research is to study the role of cyclic AMP (CAMP) in regulating intracellular communication during growth, differentiation and regression of corpora lutea. The immediate objectives are to study (1) ontogeny of contact-dependent intercellular communication among luteal cell types, and (2) effects of regulators of CAMP (e.g. luteinizing hormone, forskolin) on intracellular concentrations of CAMP and contact-dependent intercellular communication in selected luteal cells during luteal growth, differentiation and regression. %%% This is a Career Advancement Award which is one of the Research Opportunities for Women activities of the National Science Foundation. The main research interest of the awardee is the regulation of the function the corpus luteum of domestic animals, with emphasis on interactions among luteal cells during luteal growth, development, and regression. This is an important problem in reproductive physiology. This award will contribute to the advancement of the awardee's scientific career as well as to basic knowledge of the reproductive biology of domestic animals.