Doctoral Dissertation Research: Unifying Life: C.B. van Niel and the Ideals of the "Delft School" in Twentieth Century Biology

博士论文研究：统一生命：C.B.范尼尔与二十世纪生物学“代尔夫特学派”的理想

• 批准号: 9311191
• 负责人: John Lesch
• 金额: $ 1万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-07-15 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9311191&HistoricalAwards=false
• 关键词: Doctoral; Dissertation; Research; Unifying; Life

9311191 Lesch The history of biology has traditionally been the history of complex organisms. By the mid-20th century, however, a radical shift had occurred in the object of study for a significant component within biology: the object of study became microorganisms, particularly viruses and bacteria rather than the more complex organisms. This transformation resulting in the creation of molecular biology revolutionized the whole discipline of biology. Ms. Susan B. Spath, working under the direction of Dr. John Lesch, is studying one of the sources of this transformation in the so-called "Delft School" of microbiology. She is focussing her dissertation research on C. B. van Niel (1897-1985), who brought the "Delft School" ideals to the United States when he became professor at Stanford University's marine biological station in 1929. Van Niel taught for over thirty years a celebrated course in which participated a remarkable number of the major players in the development of molecular biology. Ms. Spath is assessing the impact of this course on the way biology developed in the critical period when molecular biology was first forming as a distinct research program. She is also examining the definitions of the fundamental categories of cellular life as formulated by van Niel and his student and colleague Roger Stanier in 1962. ***

9311191 Lesch 生物学的历史传统上就是复杂生物体的历史。 然而，到了 20 世纪中叶，生物学中一个重要组成部分的研究对象发生了根本性转变：研究对象变成了微生物，特别是病毒和细菌，而不是更复杂的生物体。 这种转变导致了分子生物学的诞生，彻底改变了整个生物学学科。 Susan B. Spath 女士在 John Lesch 博士的指导下，正在所谓的微生物学“代尔夫特学派”中研究这一转变的根源之一。 她的论文研究重点是 C. B. van Niel（1897-1985），他于 1929 年成为斯坦福大学海洋生物站教授，将“代尔夫特学派”的理念带到了美国。Van Niel 教授了一门著名课程三十多年，其中许多分子生物学发展的主要参与者都参与其中。 斯帕斯女士正在评估这门课程对分子生物学最初作为一个独特的研究项目形成的关键时期的生物学发展方式的影响。 她还在研究 van Niel 和他的学生兼同事 Roger Stanier 在 1962 年制定的细胞生命基本类别的定义。***