n-Pentenyl Glycosides in Mechanistic and Synthetic Investigations

本研究的重点是开发依赖于选择性保护基团的低聚糖合成方法。这项工作将理论研究与合成研究结合起来，并将弗雷泽-里德博士的“武装/解除武装”方法应用于正戊基糖苷的化学反应。有了这个更新奖，合成有机项目正在支持杜克大学化学系的Bert O. Fraser-Reid博士的研究。弗雷泽-里德教授将把他的工作重点放在低聚糖合成和理论上。寡糖是一种化合物，可以作为研究复杂碳水化合物（自然界中最普遍的分子）的机械探针。

The focus of this research is the development of synthetic methods for oligosaccharides that rely on the use of selective protecting groups. The work couples theoretical studies with synthetic studies and applies Dr. Fraser-Reid's "armed/disarmed" methodology to the chemistry of n-pentenyl glycosides. %%% With this renewal award, the Synthetic Organic Program is supporting the research of Dr. Bert O. Fraser-Reid of the Department of Chemistry at Duke University. Professor Fraser-Reid will focus his work on the synthesis and theory of the synthesis of oligosaccharides. The oligsaccharides are compounds that can serve as mechanistic probes in the study of complex carbohydrates, natures most ubiquitous molecules.