Synthesis, Reactivity and Catalysis of Novel Metallacarboranes

新型金属碳硼烷的合成、反应性和催化

• 批准号: 9314037
• 负责人: M. Frederick Hawthorne
• 金额: $ 67.3万
• 依托单位: University of California-Los Angeles
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-12-15 至 1997-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9314037&HistoricalAwards=false
• 关键词: Synthesis; Reactivity; Catalysis; Novel; Metallacarboranes

This award in the Inorganic, Bioinorganic, and Organometallic Program provides continued support for research on carboranes and metallocarboranes by Dr. M. Frederick Hawthorne of the Chemistry Department, University of California at Los Angeles. Diverse structural atomic arrangements such as "carboracycles" and "carborods" will be linked into large "supramolecular" structures. By controlling the size and shape of these clusters, cages of many different sizes, shapes, and electronic properties which can be used for capturing small ions and molecules will be constructed. Some of the most challenging target molecules will have "holes" of the appropriate size to contain three transition metal ions. In addition, the reactivity and acidity of carboranes of lanthanide metals will be investigated. The binding capabilities of electrophilic mercuracarborand hosts will be studied in a variety of new compounds in order to obtain selective anion carriers. Supramolecular structures with specific chirality and binding power will be prepared. Large new molecules of regular geometry which contain boron, carbon, and metal atoms will be synthesized. The structures are sufficiently large that they can "capture" other atoms or small molecules. Because these structures are attractive to negatively charged ions and because the size, shape, and strength of the traps can be controlled, they have great potential as "ion channels" which can transport ions in living systems. They also could be effective as analytical probes or as acid catalysts. This basic reseach is relevant to molecular recognition, homogeneous catalysis, chemic al sensor fabrication and biomolecule modification. # # ! ! ! F # # ( Times New Roman Symbol & Arial " h 1 = Margaret A. Cavanaugh Margaret A. Cavanaugh

该无机、生物无机和有机金属项目奖项为加州大学洛杉矶分校化学系的 M. Frederick Hawthorne 博士的碳硼烷和金属碳硼烷研究提供持续支持。 诸如“碳环”和“碳棒”等不同结构的原子排列将连接成大型“超分子”结构。 通过控制这些簇的尺寸和形状，将构建许多不同尺寸、形状和电子特性的笼，可用于捕获小离子和分子。 一些最具挑战性的目标分子将具有适当大小的“孔”以容纳三种过渡金属离子。 此外，还将研究镧系金属碳硼烷的反应性和酸性。 将在各种新化合物中研究亲电子汞碳硼主体的结合能力，以获得选择性阴离子载体。 将制备具有特定手性和结合力的超分子结构。 将合成含有硼、碳和金属原子的规则几何形状的大新分子。 这些结构足够大，可以“捕获”其他原子或小分子。 由于这些结构对带负电的离子具有吸引力，并且陷阱的大小、形状和强度可以控制，因此它们作为可以在生命系统中运输离子的“离子通道”具有巨大的潜力。 它们还可以有效地用作分析探针或酸催化剂。 该基础研究涉及分子识别、均相催化、化学传感器制造和生物分子修饰。 ##！ ！ ！ F # # (Times New Roman Symbol & Arial " h 1 = 玛格丽特 A. 卡瓦诺 玛格丽特 A. 卡瓦诺