Investigation of the Impact of Respiratory and GI Tract Colonization and Infection on the Origins of Allergic Asthma, Focusing on the Role of Commensal Bacteria in the GI Tract and Invasive/Non-Invasive Streptococcus Pneumoniae in the Respiratory Tract.

研究呼吸道和胃肠道定植和感染对过敏性哮喘起源的影响，重点关注胃肠道共生细菌和呼吸道中侵袭性/非侵袭性肺炎链球菌的作用。

• 批准号: 199656
• 负责人: Marcinko Josip
• 金额: $ 1.27万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-02-01 至 2011-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=199656&lang=en
• 关键词: Airway Inflammation; Allergens; Allergic Sensitization; Asthma; Commensal Intestinal Colonization; House Dust Mite; Hygiene Hypothesis; Immunology; Streptococcus Pneumoniae; Th2 Responses

The number of people with asthma worldwide has increased in each of the last four decades. In Canada, 8.4% of the population has asthma, while in the US, it is the cause over 500,000 hospitalizations and 1.5 million ER visits each year. At present, the to

过去四十年，全球哮喘患者数量逐年增加。在加拿大，8.4% 的人口患有哮喘，而在美国，每年有超过 500,000 人因哮喘住院，150 万人次到急诊室就诊。目前，至