Mechanisms of Hydrocarbon Activation and Functionalization by Soluble Transition Metal Complexes

在这个由无机、生物无机和有机金属化学项目支持的项目中，南加州大学化学系的Thomas Flood博士将进行碳氢化合物和过渡金属配合物之间反应的合成和机理研究。要研究的反应类型是所有有机金属化学和过渡金属催化的基础，目标系统提供了碳-氢、碳-碳和碳-氧键形成和/或裂解的明确例子。将评估可能影响这些反应的各种效应，特别注意胺和更常规的配体之间的比较。机械研究将使用物理和光谱方法进行。碳-氢、碳-碳和/或碳氢键在无数化学反应中断裂和/或形成，包括许多工业过程中涉及的化学反应。许多这类反应是由含金属的催化剂促进的。因此，了解金属如何介导这些过程以及它们如何与反应物质相互作用是非常重要的。这项研究将提高我们对这些重要过程的基本理解，并提供设计更有效的金属催化剂所需的信息。

In this project supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program, Dr. Thomas Flood, Chemistry Department, University of Southern California, will undertake synthetic and mechanistic studies of reactions between hydrocarbons and transition metal complexes. The reaction types to be investigated are fundamental to all of organometallic chemistry and transition metal-based catalysis with the targeted systems providing well-defined examples in which carbon-hydrogen, carbon-carbon, and carbon-oxygen bonds are formed and/or cleaved. A variety of effects which may influence these reactions will be evaluated, with particular attention being paid to a comparison between amine and more conventional ligands. Mechanistic studies will be carried out using physical and spectroscopic methods. Carbon-hydrogen, carbon-carbon, and/or carbon-hydrogen bonds are broken and/or formed in countless chemical reactions, including those involved in many industrial processes. A large number of these reactions are facilitated by metal containing catalysts. Consequently, an understanding of how metals mediate such processes and how they interact with reacting species is of profound importance. This research will both improve our fundamental understanding of these important processes and provide the information needed to design more efficient metal catalysts.