Mechanisms of Hydrocarbon Activation and Functionalization by Soluble Transition Metal Complexes

在这个由无机，生物无机， 有机化学项目，托马斯洪水博士，化学系， 南加州大学，将进行合成和 烃类与过渡态反应的机理研究 金属配合物要研究的反应类型是基本的， 所有的有机金属化学和过渡金属基催化剂， 目标系统提供了定义明确的示例，其中 形成碳-氢、碳-碳和碳-氧键，和/或 劈开的可能影响这些反应的各种效应将是 评价，特别注意比较 胺和更常规的配体。将进行机理研究 用物理和光谱学的方法。 碳-氢键、碳-碳键和/或碳-氢键断裂 和/或在无数的化学反应中形成， 在许多工业过程中。这些反应中有许多是 通过含金属的催化剂促进。因此，理解 金属如何介导这些过程以及它们如何与反应相互作用 物种是非常重要的。这项研究将提高我们的 对这些重要过程的基本理解，并提供 设计更高效的金属催化剂所需的信息。

In this project supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program, Dr. Thomas Flood, Chemistry Department, University of Southern California, will undertake synthetic and mechanistic studies of reactions between hydrocarbons and transition metal complexes. The reaction types to be investigated are fundamental to all of organometallic chemistry and transition metal-based catalysis with the targeted systems providing well-defined examples in which carbon-hydrogen, carbon-carbon, and carbon-oxygen bonds are formed and/or cleaved. A variety of effects which may influence these reactions will be evaluated, with particular attention being paid to a comparison between amine and more conventional ligands. Mechanistic studies will be carried out using physical and spectroscopic methods. Carbon-hydrogen, carbon-carbon, and/or carbon-hydrogen bonds are broken and/or formed in countless chemical reactions, including those involved in many industrial processes. A large number of these reactions are facilitated by metal containing catalysts. Consequently, an understanding of how metals mediate such processes and how they interact with reacting species is of profound importance. This research will both improve our fundamental understanding of these important processes and provide the information needed to design more efficient metal catalysts.