Mechanisms of Activation and Oxygenation of Alkanes by Soluble Transition Metal Complexes

可溶性过渡金属配合物对烷烃的活化和氧化机理

• 批准号: 0209079
• 负责人: Thomas Flood
• 金额: $ 39万
• 依托单位: University of Southern California
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0209079&HistoricalAwards=false
• 关键词: Mechanisms; Activation; Oxygenation; Alkanes; Soluble

This award by the Inorganic, Bioinorganic and Organometallic Chemistry program supports research by Thomas C. Flood, Department of Chemistry, University of Southern California, in fundamental studies of alkane activation and functionalization. They are particularly interested in understanding the weak interactions of alkanes with electrophilic metal centers. These sigma complexed alkane intermediates may play a key role in many primary reactions involved in catalysis. One catalytic transformation Flood is concentrating on is the oxidation of methane to methanol using a rhodium or osmium catalyst. A flexible triamine ligand such as 1,4,7-triazacyclononane (tacn or Cn) complexes and stabilizes the catalyst and will not decompose under the reaction conditions New catalysts and processes may be designed as a result of detailed understanding of the way alkanes interact with metal centers,. The efficient conversion of alkanes to alcohols is a longstanding goal of the chemical industry. Students will be trained in the synthesis, characterization and mechanistic studies of these potential catalysts and catalyst precursors.

这项由无机化学、生物无机化学和金属有机化学项目颁发的奖项支持南加州大学化学系Thomas C.Flood在烷烃活化和官能化基础研究方面的研究。他们对了解烷烃与亲电金属中心的弱相互作用特别感兴趣。这些Sigma络合的烷烃中间体可能在许多涉及催化的初级反应中发挥关键作用。Flood专注于的一种催化转化是使用Rh或Om催化剂将甲烷氧化为甲醇。一种灵活的三胺配体，如1，4，7-三氮杂环酮(TACN或CN)络合物，稳定催化剂，在反应条件下不会分解。由于对烷烃与金属中心相互作用的详细了解，可能会设计出新的催化剂和工艺。有效地将烷烃转化为醇是化学工业的长期目标。学生将接受这些潜在催化剂和催化剂前体的合成、表征和机理研究方面的培训。