Aqueous Solution Organometallic Chemistry Directed toward Alkene Hydration and Amination

在无机化学、生物无机化学和有机金属化学计划中，这个环境友好的化学合成和加工项目致力于发现可用于开发新的过渡金属催化的反应，分别用于水溶液和液氨溶液中的烯烃水合和胺化反应。预计这种工艺将最大限度地减少醇或胺合成过程中产生的有机废物量。具体目标包括合成将在水和液氨中提供溶解性的8族金属配体的新络合物，以及鉴定将激活这些溶剂的O-H和N-H键的络合物。要采用的一种策略是水或氨的阳离子络合物与相同或不同第8族金属的低价络合物的氧化加成反应。核磁共振波谱将被用来检测氢化物络合物。化学工业的一个主要目标是最大限度地减少需要处置或焚烧的废物。有机金属化合物在许多重要的工业过程中用作催化剂；然而，所有这些都使用有机溶剂。使用水或其他容易提纯的材料(如液氨)作为溶剂，可能有助于将此类浪费降至最低。这项研究的目的是探索在水或液氨中进行有机金属化学的可能性。路易斯安那州巴吞鲁日的乙基公司正在合作这一项目。

This Environmentally Benign Chemical Synthesis and Processing project, in the Inorganic, Bioinorganic and Organometallic Chemistry Program, is concerned with the discovery of reactions that can be used in the development of new transition metal catalyzed reactions for hydration and amination of olefins in aqueous and liquid ammonia solutions, respectively. It is anticipated that such processes would minimize the amount of organic waste that would be generated in the synthesis of alcohols or amines. Specific aims include the synthesis of new complexes of groups 8 metals of ligands that will provide for solubility in water and liquid ammonia, and the identification of complexes that will activate the O-H and N-H bonds of these solvents. One strategy to be employed is the oxidative addition reaction of a cationic complex of water or ammonia with a low-valent complex of the same or a different group 8 metal. NMR spectroscopy will be used to detect hydride complexes. A major objective in the chemical industry is the minimization of waste materials that require disposal or incineration. Organometallic compounds are used as catalysts in a number of important industrial processes; however, all of these use organic solvents. The use of water, or other easily purified materials such as liquid ammonia, as solvents is one way that may help to minimize such waste. The objective of this research is to explore the possibility that organometallic chemistry can be done in water or liquid ammonia. Ethyl Corporation, Baton Rouge, Louisiana, is collaborating on this project.