Purchase of a New 400 MHz Liquid Phase NMR Spectrometer

该奖项由化学研究仪器和设施 （CRIF）计划将协助化学和生物化学系 德克萨斯理工大学购买了一台400兆赫的液相核 磁共振（NMR）光谱仪。 该设备将增强 在以下几个方面进行了研究：（1）共价键 通过奎宁海绵代谢物修饰抗原肽 （2）Pupehenone的合成及固溶体结构 生物活性物质P类似物，（3）合成有机宿主， 离子客体的识别;（4）不对称反应的催化剂 （5）紫杉醇衍生物的合成。 核磁共振 (NMR)光谱学是化学家可以利用的最有力的工具， 分子结构的阐明。用于标识 未知物质，表征内部原子的特定排列 分子，并研究分子之间的相互作用的动力学， 溶液获得最先进的核磁共振光谱分析是必不可少的 从事前沿研究的化学家。结果从这些 NMR研究在诸如聚合物、催化剂和聚合物等领域是有用的。 生物学

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program will assist the Department of Chemistry and Biochemistry at Texas Tech University to purchase a 400 MHz liquid phase nuclear magnetic resonance (NMR) spectrometer. This equipment will enhance research in a number of areas such as the following: (1) covalent modification of antigenic peptides by the quinonoid sponge metabolite puupehenone, (2) synthesis and solid solution phase structures of biologically active substance P analogs, (3) synthetic organic hosts for the recognition of ionic guests, (4) catalysts for asymmetric reactions and (5) the synthesis of taxol derivatives. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers, catalysis, and in biology.