Investigation of RNAi strategies to treat Retinoblastoma and other ocular diseases
Investigation of RNAi strategies to treat Retinoblastoma and other ocular diseases
批准号:
200987
负责人:
McCurdy Sean
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-02-01 至 2011-02-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Retinoblastoma is most common ocular cancer and caused by mutations in the RB1 gene. Retinoblastoma protein (Rb), coded by the RB1 gene, inhibits activating E2Fs (1-3), which are required for DNA synthesis. Conversely, Rb activity is inhibited via hyperph
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A novel use of E2f and Cdk inhibitors to prevent RB1-null tumors in genetically engineered models of retinoblastoma and other cancers
-
批准号:274466
-
项目类别:Studentship Programs
-
资助金额:$10.93万
-
财政年份:2012
-
负责人:McCurdy Sean
-
依托单位:
海外基金