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Investigation of RNAi strategies to treat Retinoblastoma and other ocular diseases

Investigation of RNAi strategies to treat Retinoblastoma and other ocular diseases
治疗视网膜母细胞瘤和其他眼部疾病的 RNAi 策略研究
批准号:
200987
负责人:
McCurdy Sean
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-02-01 至 2011-02-01

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中文摘要
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英文摘要
Retinoblastoma is most common ocular cancer and caused by mutations in the RB1 gene. Retinoblastoma protein (Rb), coded by the RB1 gene, inhibits activating E2Fs (1-3), which are required for DNA synthesis. Conversely, Rb activity is inhibited via hyperph
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A novel use of E2f and Cdk inhibitors to prevent RB1-null tumors in genetically engineered models of retinoblastoma and other cancers
  • 批准号:
    274466
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $10.93万
  • 财政年份:
    2012
  • 负责人:
    McCurdy Sean
  • 依托单位:
海外基金