Synthetic Applications of Photocycloadditions

本研究的重点是研究取代对分子内烯-烯烃光环加成系链的立体化学控制作用。这些光产物将作为合成各种天然产物类型的前体，包括紫杉素、麦哲伦胺酮、丝氨酸和鹿脂醇。有了这个更新奖，合成有机项目正在支持北卡罗来纳大学教堂山分校化学系的迈克尔·t·克里明斯博士的研究。克里明斯教授将把他的工作重点放在利用光环加成物合成一些有趣的天然产物上。＊＊＊

9319512 Crimmins The focus of this research is the study of the effects of substitution on the tethering chain in intramolecular enone-olefin photocycloadditions with regard to stereochemical control. The photoproducts will serve as precursors for the synthesis of a variety of natural product types including taxusin, magellaninone, serratinine and lubiminol. %%% With this renewal award, the Synthetic Organic Program is supporting the research of Dr. Michael T. Crimmins of the Department of Chemistry at the University of North Carolina, Chapel Hill. Professor Crimmins will focus his work on the use of photocycloadditons for the synthesis of a number of interesting natural products. ***