MRI: Acquisition of a 600 MHz Spectrometer with Cryogenic Probe

MRI：获取带有低温探头的 600 MHz 光谱仪

• 批准号: 0922858
• 负责人: Michael Crimmins
• 金额: $ 70.66万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-15 至 2012-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922858&HistoricalAwards=false
• 关键词: MRI; Acquisition; 600; MHz; Spectrometer

With this award from the Major Research Instrumentation (MRI) program, Michael T. Crimmins, Maurice S. Brookhart, Michel R. Gagne, Gary J. Pielak and Marcey Waters in the Department of Chemistry at the University of North Carolina, Chapel Hill will acquire a 600 MHz NMR spectrometer with a cryogenic probe for use in the development of new and efficient methods of synthesis of complex organic molecules such as the asymmetric synthesis of polyketides and medium ring ethers. It will be used to advance research projects in bio-organic synthesis, organic and inorganic catalysis, and molecular recognition.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential for chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.

有了这个主要研究仪器（MRI）计划的奖项，迈克尔T。莫里斯·布雷明斯布鲁克哈特位于查佩尔山的北卡罗来纳州大学化学系的加涅、加里J.皮拉克和马西沃茨将获得一台带有低温探针的600 MHz NMR光谱仪，用于开发合成复杂有机分子的新的有效方法，如聚酮化合物和中环醚的不对称合成。核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一，它将被用于推进生物有机合成、有机和无机催化以及分子识别的研究项目。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学和生物化学产生影响。该仪器将成为教学和研究的一个组成部分。