SGER: Effects of Thyroxine on Peripheral Imprinting
SGER:甲状腺素对外周印记的影响
基本信息
- 批准号:9320702
- 负责人:
- 金额:$ 5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:1994
- 资助国家:美国
- 起止时间:1994-02-01 至 1995-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
WPC_ 2 B V P Z Courier 10cpi ? x x x , k x 6 X @ 8 ; X @ HP LaserJet III HPLASEII.PRS x @ , t 0 OpX @ 2 Z L ! #| x Canon LBP-8III (Letterhead) CALB8IAD.PRS x @ 0 jFX @ Courier 10cpi Courier 10cpi Bold 2 X . ? x x x , l x 6 X @ 8 ; X @ l ? x x x , x ` w ; X ' 9 N ( ı 5 6N E 2 D u | u | t D 5 t$ D E =& t =^ u y r= u t " s r 9320702 Roberts Salmons are well known for their ability to return to the stream in which they were born. The sensory basis for this remarkable behavior is olfactory: during a sensitive developmental period (smolt transformation), salmon imprint to distinctive homestream odors, and adults later use this odorant memory as a migratory cue to guide them back from the open ocean to their natal streams. How salmon imprint to homestream odors has remained an important but perplexing puzzle for over forty years. Proponents of olfactory imprinting have assumed that the olfactory memory for the home stream resides in the central nervous system. Dr. Roberts, however, proposes that olfactory memory is actually retained in the olfactory receptor cells themselves. The basis for his theory rests on two important findings. First, surges in plasma thyroxine levels mediate smolting, and second, olfactory imprinting coincides with this developmental metamorphosis. This small grant for exploratory research enables Dr. Roberts to use state of the art electrophysiological and neuroanatomical techniques to determine whether there are thyroxine induced change s in olfactory receptor neurons to specific odors. This basic research will have direct benefits to Pacific salmon by providing insight into how olfactory imprinting might be artificially manipulated. If thyroxine hormone can influence the ability of fish to imprint during a wider time frame than smolting, this finding could markedly advance conservation efforts aimed at transporting rapidly diminishing endangered salmon runs to healthier river systems. ***
公司简介 2 B V P Z 10cpi ? x x x, K x 6 X @ 8 ; X @ 惠普LaserJet III HPLASEII.PRS X @ , t 0 OpX @ 2 Z L ! #|X Canon LBP-8III(Letterhead) CALB8IAD.PRS X @ 联系我们 10 cpi 10 cpi粗体 2 X . ? x x x, L x 6 X @ 8 ; X @ L ? x x x, X w ; X ' 9 N ( ı 5 6N E 2 D u| u|不 D 5 不是$ D E = t =^ u y r= u t“ S R 小行星9320702 三文鱼以其能够回到它们出生的溪流中而闻名。 这种非凡行为的感官基础是嗅觉:在敏感的发育期(小鲑鱼转变),鲑鱼对独特的家乡气味留下印记,成年鲑鱼后来使用这种气味记忆作为迁移线索,引导它们从开阔的海洋回到纳塔尔的河流。 鲑鱼如何对家乡的气味留下印记,四十多年来一直是一个重要但令人困惑的难题。 嗅觉印记的支持者们认为,对主流的嗅觉记忆存在于中枢神经系统中。 然而,罗伯茨博士提出,嗅觉记忆实际上保留在嗅觉受体细胞本身。 他的理论基于两个重要发现。 第一,激增的血浆甲状腺素水平介导的闷烧,第二,嗅觉印记与这种发展变态。 这项探索性研究的小额资助使Roberts博士能够使用最先进的电生理学和神经解剖学技术来确定是否存在甲状腺素诱导的嗅觉受体神经元对特定气味的变化。 这项基础研究将直接有利于太平洋鲑鱼提供洞察如何嗅觉印迹可能是人工操纵。 如果甲状腺素激素可以影响鱼类在更广泛的时间范围内留下印记的能力,这一发现可以显着推进旨在将迅速减少的濒危鲑鱼运输到更健康的河流系统的保护工作。 ***
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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William Roberts其他文献
AN UNUSUAL CASE OF SERIAL LEFT VENTRICULAR OUTFLOW OBSTRUCTION: COINCIDENT HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY AND SUBAORTIC MEMBRANE MANAGED OPERATIVELY
- DOI:
10.1016/s0735-1097(19)33333-9 - 发表时间:
2019-03-12 - 期刊:
- 影响因子:
- 作者:
Andy Lee;Aaron Mercado-Reza;Clay Barbin;Zachary Rosol;Nishi Patel;Ari Cedars;William Roberts;Robert Hebeler;Amarinder Bindra - 通讯作者:
Amarinder Bindra
Pediatric Laboratory Medicine
儿科检验医学
- DOI:
10.1309/c52d-by0u-vxxu-r360 - 发表时间:
2002 - 期刊:
- 影响因子:0
- 作者:
C. Coffin;M. Hamilton;T. Pysher;P. Bach;E. Ashwood;Jeanne Schweiger;D. Monahan;Deborah A Perry;B. Rogers;C. Brugnara;J. Rutledge;R. Weiss;O. Ash;Harry Hill;W. Meikle;William Roberts;S. Geaghan - 通讯作者:
S. Geaghan
Effects of a Unique Hematology-Oncology Pediatric Palliative Care Program On Medical Decision-Making and Communication Between Healthcare Providers and Families (733)
- DOI:
10.1016/j.jpainsymman.2011.12.211 - 发表时间:
2012-02-01 - 期刊:
- 影响因子:
- 作者:
Deborah Schiff;Cassie Kline;JoAnne Auger;Jennifer Willert;William Roberts;Anke Reineke - 通讯作者:
Anke Reineke
ROLE OF HEART TRANSPLANT FOR VT ELECTRICAL STORM IN AN ORTHOTROPIC LIVER TRANSPLANTED PATIENT
- DOI:
10.1016/s0735-1097(20)33175-2 - 发表时间:
2020-03-24 - 期刊:
- 影响因子:
- 作者:
Justin Arunthamakun;Amit Alam;Joshua James Rutland;Alan Donsky;William Roberts;Melody Sherwood;Timothy Gong;Praveen Rao;Shelley Hall - 通讯作者:
Shelley Hall
FULMINANT RHEUMATOID HEART DISEASE
- DOI:
10.1016/s0735-1097(19)33461-8 - 发表时间:
2019-03-12 - 期刊:
- 影响因子:
- 作者:
Jessica Meyer;Clay Barbin;S. Shiva Patlolla;Joseph Guileyardo;William Roberts;Georges Feghali - 通讯作者:
Georges Feghali
William Roberts的其他文献
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{{ truncateString('William Roberts', 18)}}的其他基金
EFRI HyBi: Algal Oils to 'Drop-in' Replacements for Petroleum-derived Transportation Fuels
EFRI HyBi:藻油可“直接”替代石油衍生运输燃料
- 批准号:
0937721 - 财政年份:2009
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
Experimental and Numerical Investigation of the Mechanisms of Local Extinction Using Flame Kernel-Vortex Interactions
利用火焰核-涡旋相互作用对局部消光机制进行实验和数值研究
- 批准号:
0237406 - 财政年份:2003
- 资助金额:
$ 5万 - 项目类别:
Continuing Grant
Equipment to Sustain Combustion Research at NC State
北卡罗来纳州立大学维持燃烧研究的设备
- 批准号:
0111426 - 财政年份:2001
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
CAREER: Influence of Unsteady Stretch on Premixed Flame Kernel Growth
事业:不稳定拉伸对预混火焰核生长的影响
- 批准号:
9702277 - 财政年份:1997
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
Thyroid Hormone Effects on the Peripheral Olfactory System
甲状腺激素对周围嗅觉系统的影响
- 批准号:
9410637 - 财政年份:1995
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
Mathematical Sciences Computing Research Environments
数学科学计算研究环境
- 批准号:
9106029 - 财政年份:1991
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
Theoretical Studies of the Structure and Dynamics of Cloudy Interstellar Medium Spiral Galaxies
云状星际介质螺旋星系结构与动力学的理论研究
- 批准号:
8712084 - 财政年份:1988
- 资助金额:
$ 5万 - 项目类别:
Continuing Grant
Acquisition of Mathematical Sciences Research Equipment
数学科学研究设备购置
- 批准号:
8304459 - 财政年份:1983
- 资助金额:
$ 5万 - 项目类别:
Standard Grant
Galaxies, the Interstellar Medium, the External Environment:Galactic Gas Dynamics and Evolutionary Simulations
星系、星际介质、外部环境:星系气体动力学和演化模拟
- 批准号:
8204256 - 财政年份:1982
- 资助金额:
$ 5万 - 项目类别:
Continuing Grant
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