Investigation of the Retinoblastoma gene using fruit flies as a model organism

使用果蝇作为模式生物研究视网膜母细胞瘤基因

• 批准号: 213312
• 负责人: Moon Nam S
• 金额: $ 21.86万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2015-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=213312&lang=en
• 关键词: Apoptosis; Cancer; Cell Cycle; Drosophila Genetics; Rb/E2f

Accumulation of hazardous mutations is responsible for cancer development. Many genes prone to mutation in cancer are evolutionarily conserved, and their homologs have been identified in different species. Rb was the first identified tumor suppressor gene

危险突变的积累是癌症发展的原因。许多在癌症中容易发生突变的基因在进化上是保守的，它们的同源基因已经在不同的物种中被鉴定出来。Rb是第一个被发现的肿瘤抑制基因