Identification and in vivo characterization of pharmacological chaperones of the dopamine transporter

多巴胺转运蛋白药理学伴侣的鉴定和体内表征

• 批准号: 225375
• 负责人: Beerepoot Pieter
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-02-01 至 2012-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=225375&lang=en
• 关键词: Animal Models Of Mental Illness; Behavioural Assay; Dopamine; Dopamine Transporter; Elisa Cell Surface Expression Assay; Glutamate; Pharmacological Chaperone; Protein Folding; Schizophrenia; Transgenic Mice

Schizophrenia is a mental illness affecting 0.7% of people in Canada, and is characterized by hallucinations, delusions as well as reduced emotional response and motivation. Due to the severity of the symptoms and chronic nature of this illness, schizophr

精神分裂症是一种精神疾病，影响加拿大0.7%的人，其特征是幻觉，妄想以及情绪反应和动机减少。由于这种疾病的症状和慢性性质的严重性，