Colonic Goblet Cell Mediators: Active Players in Host Defense and Mucosal Protection?

结肠杯状细胞介体：宿主防御和粘膜保护的活跃参与者？

• 批准号: 224622
• 负责人: Vallance Bruce A
• 金额: $ 41.94万
• 依托单位: BC Children's Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=224622&lang=en
• 关键词: Animal Modeling; Attaching/Effacing Bacteria; Epithelium; Gastroenterology; Goblet Cells

The colonic epithelium consists of both absorptive cells as well as secretory goblet cells that produce mucus. While many damaging agents, including bacterial pathogens target the epithelium, bacteria must first cross the sticky mucus layer that covers an

结肠上皮既有吸收细胞，也有分泌粘液的杯状细胞。虽然包括细菌病原体在内的许多破坏性因素都以上皮为目标，但细菌必须首先穿过覆盖在皮肤上的粘液层。