Oil-Water Interfacial Synthesis as a Benign and Safer Alternative to Conventional Liquid-Phase Syntheses

建议编号：CTS-9414672 P.I.：P.K.Lim首席调查员将在4月27-29日在南卡罗来纳州斯帕坦堡举行的“清洁先生”会议上介绍由美国国家科学基金会赞助的一个项目的研究成果。目标是实现一种对环境无害的新合成技术的商业采用。这项新的合成技术是基于一项由美国国家科学基金会资助的研究成果，名为《油水界面合成作为传统液体合成的良性且更安全的替代方案》。界面反应技术通过将无害的油水混合物与表面活性催化剂复合体结合使用，避免了对有毒或危险溶剂的需要。表面活性配体被用来将催化剂吸引到油-水界面，在那里催化剂影响反应，并在那里也可以回收。新技术与传统的相转移反应技术的不同之处在于，反应发生在界面上，而不是在体相中。除了对环境友好外，界面合成技术还具有催化剂回收容易、反应活性和选择性高(通常与均相催化有关)和易于操作的优点。该新技术已成功地应用于2，6-二甲基苯酚的偶联聚合。在温和的反应条件下，以较高的产率(85%)获得了高相对分子质量的聚苯醚。详细的动力学结果将在会议上公布。

ABSTRACT Proposal Number: CTS-9414672 P.I.: P.K. Lim The principle investigator is presenting the research findings of an NSF-sponsored project at the "Mr. Clean" Conference that is to be held at Spartanburg, SC on April 27-29. The goal is to effect the commercial adoption of a new synthesis technique that is environmentally benign. The new synthesis technique is based on research, entitled "Oil-Water Interfacial Synthesis as a Benign and Safer Alternative to Conventional Liquid-Phase Syntheses," that has been funded by the NSF. The interfacial reaction technique avoids the need for toxic or hazardous solvents by using an innocuous oil-water mixture in conjunction with a surface-active catalyst complex. A surface-active ligand is used to draw the catalyst to the oil-water interface, where the catalyst effects the reaction and where it can also be recovered. The new technique differs from conventional phase-transfer reaction technique in that the reaction occurs at the interface, rather than in one of the bulk phases. Aside from being environmentally benign, the interfacial synthesis technique also offers the advantages of easy catalyst recovery, high reactivity and selectivity that is normally associated with homogenous catalysis, and ease of operation. The new technique has been successfully demonstrated on the coupling polymerization of 2, 6-dimethylphenol. high molecular-weight poly (phenylene oxide) has been obtained in a high yield (85%) under mild reaction conditions. Detailed kinetic results will be presented at the conference.