Mechanism-based sialidase inhibitors as potential therapeutics for influenza and trypanosomal diseases

基于机制的唾液酸酶抑制剂作为流感和锥虫病的潜在治疗方法

• 批准号: 180418
• 负责人: Withers Stephen G
• 金额: $ 40.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-03-01 至 2014-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=180418&lang=en
• 关键词: Antivirals; Chagas; Influenza; Inhibitors; Sialidase; Trypanosomes

The development of therapies for treatment of viral diseases has proved to be much more challenging than for bacterial infections. Despite stunning successes such as the AIDS drugs, the development of resistant virus strains has generally required use of

治疗病毒性疾病的疗法的开发已被证明比细菌感染更具挑战性。尽管艾滋病药物取得了惊人的成功，但耐药病毒株的开发通常需要使用