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Extending circulation time of protein therapeutics by capping glycan structures with 7F-Sialic acids

Extending circulation time of protein therapeutics by capping glycan structures with 7F-Sialic acids
通过用 7F-唾液酸封端聚糖结构来延长蛋白质治疗剂的循环时间
批准号:
315109
负责人:
Withers Stephen G
金额:
$11.65万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-09-01 至 2015-09-01

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中文摘要
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英文摘要
The vast majority of therapeutic drugs that have been used to treat illnesses over the past one hundred years and more have been small molecules. These typically inhibit specific enzymes or block particular receptors to have a therapeutic effect. Another
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Improved organ transplant across the ABO barrier through enzymatic removal of antigens
  • 批准号:
    415710
  • 项目类别:
    Operating Grants
  • 资助金额:
    $31.42万
  • 财政年份:
    2019
  • 负责人:
    Withers Stephen G
  • 依托单位:
Towards new therapeutics through manipulation of glyco-enzymes
  • 批准号:
    333599
  • 项目类别:
    Operating Grants
  • 资助金额:
    $108.92万
  • 财政年份:
    2015
  • 负责人:
    Withers Stephen G
  • 依托单位:
Novel Influenza Neuraminidase Inhibitors - Development of Orally Bioavailable Agents
  • 批准号:
    256774
  • 项目类别:
    Operating Grants
  • 资助金额:
    $21.64万
  • 财政年份:
    2012
  • 负责人:
    Withers Stephen G
  • 依托单位:
Mechanism-based sialidase inhibitors as potential therapeutics for influenza and trypanosomal diseases
  • 批准号:
    180418
  • 项目类别:
    Operating Grants
  • 资助金额:
    $40.27万
  • 财政年份:
    2009
  • 负责人:
    Withers Stephen G
  • 依托单位:
海外基金