Identification of early epigenomic changes produced by oncogenic mutant KRAS in transduced normal human mammary cells

鉴定致癌突变体 KRAS 在转导的正常人乳腺细胞中产生的早期表观基因组变化

• 批准号: 367820
• 负责人: Tan Susanna Shu Xia
• 金额: $ 7.65万
• 依托单位: BC Cancer, part of PHSA (Vancouver)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-10-01 至 2019-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367820&lang=en
• 关键词: Breast Cancer; Breast Cancer Modelling; Epigenomics; Mammary Epithelium; Mammary Stem Cell; Oncogene; Sequencing; Tumourigenesis

Breast cancers are extremely complex diseases with fatal outcomes in thousands of women annually in Canada and millions worldwide. In any single person, the prognosis is affected by many factors. This is due, in part, to the fact that breast cancers desti

乳腺癌是一种极其复杂的疾病，加拿大每年有数千名妇女死亡，全世界有数百万人死亡。在任何一个人，预后受到许多因素的影响。这部分是由于乳腺癌的命运，