Microscopy in the Chemical Senses

这个小组的提案寻求资金来购买三个主要项目的设备：一个低温恒温器、一个化合物、研究级显微镜和一个共焦显微镜。这些物品将被安置在莫内尔化学传感中心的组织学设施中，并将在整个中心范围内使用。该设备应八个主要用户的要求，用于旨在更全面地理解化学感官的研究项目。这些项目利用标准的组织学、凝集素和免疫组织化学、原位杂交和原位聚合酶链式反应，并集中在一系列问题上，从外周感觉受体细胞中蛋白质和核苷酸的细胞内定位到大型器官系统内的代谢活动，例如大脑和肝脏。

This group proposal seeks funds to purchase three major items of equipment: a cryostat, a compound, research-grade microscope and a confocal microscope. These items will be housed in the Histological Facility at the Monell Chemical Senses Center and will be utilized Center-wide. The equipment is requested by eight major users for research programs directed at a fuller understanding of the chemical senses. The projects utilize standard histology, lectin and immuno-histochemistry, in situ hybridization and in situ PCR, and focus on a range of issues from intracellular localization of proteins and neucleotides in peripheral sensory receptor cells to metabolic activity within large organ systems, e.g. the brain and the liver.