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Discovering new high-risk ovarian cancer predisposing genes through targeted genetic analyses of a Canadian founder population

Discovering new high-risk ovarian cancer predisposing genes through targeted genetic analyses of a Canadian founder population
通过对加拿大创始人群进行有针对性的遗传分析，发现新的高风险卵巢癌易感基因
批准号：
370298
负责人：
Tonin Patricia N
金额：
$49.6万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=370298&lang=en
关键词：
Biobanks Cancer Predispositon Cancer Prevention Dna Sequencing Exome Sequencing Founder Populations Germline Mutations, Hereditary Cancer, Mutation Screening Ovarian Cancer

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Since the discovery of the BRCA1 and BRCA2 genes over 20 years ago, research has shown that carriers of mutations in these genes significantly increases their risk for ovarian cancer. Cancer prevention studies have since shown that the removal of ovaries
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