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NSF Young Investigator: Dynamics of Complex Chemical Systems

NSF Young Investigator: Dynamics of Complex Chemical Systems
NSF 青年研究员:复杂化学系统的动力学
批准号:
9457970
负责人:
Martin Gruebele
金额:
$31.25万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-07-15 至 2000-06-30

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中文摘要
翻译
Gruebele将利用超快激光技术和高分辨率光源来研究复杂化学反应的动力学。该研究的具体目标是研究途径选择性离子-分子反应,更好地理解能量松弛,以便在大分子中控制反应,以及更好地理解生物聚合物的动力学。这个研究项目的结果将帮助那些试图通过更好地理解驱动化学反应的因素来指导化学反应可能采取的途径的科学家。另一个结果是更好地理解生物分子(如蛋白质)如何折叠成其独特的分子结构。这种理解有各种各样的应用,包括针对特定任务定制药物的能力。
英文摘要
In this NSF Young Investigator Award in the Physical Chemistry Program of the Chemistry Division, Gruebele will use ultrafast laser techniques and high resolution sources to study the dynamics of complex chemical reactions. Specific goals of the research are the study of pathway-selective ion-molecule reactions, a better understanding of energy relaxation to allow reaction control in large molecules, and a better understanding of the dynamics of biopolymers. %%% The results of this research project will aid scientist who are attempting to direct the pathways which can be taken by chemical reactions by allowing a better understanding of what drives chemical reactions. Another result is a better understanding of how biological molecules such as proteins fold into their unique molecular configurations. Such an understanding has a variety of applications, including the ability to tailor medicines for specific tasks.
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会议论文
Acquisition of Two-Color 3-D Minflux for Live-Cell Single Molecule Imaging and Tracking at Unprecedented Spatial and Temporal Resolution
Protein dynamics: from the marginally to the extremely stable
Dynamics and equilibria of weak in-cell interactions
Coupling protein dynamics and cell dynamics
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