U.S.-Netherlands Cooperative Research in Developmental Neurobiology

美国-荷兰发育神经生物学合作研究

• 批准号: 9500488
• 负责人: Gerald Eagleson
• 金额: $ 0.83万
• 依托单位: Loras College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-08-01 至 1996-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9500488&HistoricalAwards=false
• 关键词: U.S.; Netherlands; Cooperative; Research; Developmental

This award provides partial support for Professor Gerald Eagleson of Loras College to spend several months collaborating in developmental neurobiology research with Bruce Jenks and others of the Institute of Neuroscience of the University of Nijmegen, The Netherlands and with Dr. A. J. Dunston of the University of Utrecht. Their joint research will focus on the factors which influence the early development of the area of the amphibian brain which ultimately becomes the hypothalamo-pars intermedia complex. The participating research groups in the Netherlands have substantial experience and extensive facilities for investigating the morphological and physiological aspects of this complex in the adult amphibian, Xenopus. Dr. Eagleson has done landmark work on the embryological development of the amphibian brain and pituitary gland, ranging from microdissection and mapping to experimental studies of gene expression and inductive agents between various tissues. This proposed collaboration brings together a unique blend of complementary expertise from the U.S. and Europe to study the origin of the functional relationship between the brain and the pituitary. The results of the research to be carried out by Dr. Eagleson and his colleagues will be a fundamental contribution to our understanding of the development of this neuroendocrine feedback system.

该奖项为洛拉斯学院的Gerald Alberleson教授提供了部分支持，使其能够与荷兰奈梅亨大学神经科学研究所的布鲁斯詹克斯和其他人以及A.乌得勒支大学的J·邓斯顿说。 他们的联合研究将集中在影响两栖动物大脑区域早期发育的因素上，该区域最终成为下丘脑-中间部复合体。 荷兰的参与研究小组拥有丰富的经验和广泛的设施，可以调查成年两栖动物非洲爪蟾的这种复合体的形态和生理方面。 Dr. Elleson在两栖动物大脑和脑垂体的胚胎发育方面做了具有里程碑意义的工作，从显微解剖和绘图到各种组织之间基因表达和诱导剂的实验研究。 这项拟议的合作汇集了来自美国和欧洲的互补专业知识，以研究大脑和垂体之间功能关系的起源。 Dr. Melleson和他的同事们将要进行的研究结果将对我们理解这种神经内分泌反馈系统的发展做出根本性的贡献。