Career Program: Research and Education in Chemical Engineering and Biotechnology

职业计划：化学工程和生物技术的研究和教育

• 批准号: 9502184
• 负责人: Todd Przybycien
• 金额: $ 28.5万
• 依托单位: Rensselaer Polytechnic Institute
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-06-15 至 1999-04-09
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9502184&HistoricalAwards=false
• 关键词: Career; Program; Research; Education; Chemical

9502184 Przybycien This project is on research to study protein aggregation. One area of focus is on the structural characterization of protein aggregates. This will include the development of new information on the mechanism of aggregate formation, the impact of environmental conditions or process parameters on aggregation, and the ease of reconstitution of aggregates. Another area of focus is on the identification of specific interaction sites in protein aggregates. The ultimate goal is to obtain predictive ability for the propensity of proteins to aggregate and protein- specific strategies for the promotion or inhibition of aggregation in cellular, production and storage environments. In addition to this research activity, the investigator will enhance education by engaging in activities to produce instructional innovation, curricular synergy, and educational excitement. ***

9502184 Przybycien该项目是研究蛋白质聚集的研究。 一个重点领域是蛋白质聚集体的结构表征。 这将包括开发关于聚集体形成机制、环境条件或工艺参数对聚集体的影响以及聚集体重组难易程度的新信息。 另一个重点领域是识别蛋白质聚集体中的特定相互作用位点。 最终目标是获得蛋白质聚集倾向的预测能力和促进或抑制细胞、生产和储存环境中聚集的蛋白质特异性策略。 除了这项研究活动，研究人员将通过参与活动，以产生教学创新，课程协同作用和教育兴奋，以加强教育。 ***