Small Grants for Exploratory Research: Conducting Polymer Chromatography for Protein Separations

这个SGER项目探索了电化学色谱从涂覆导电聚合物的颗粒基板到整体结构的扩展。径向流动单元将由涂有导电聚合物（例如聚n -烷基吡咯）的多孔网状玻璃碳制成，并测试具有不同等电点的模型蛋白质的结合能力和可逆结合。离子交换色谱在通量、分离效率和试剂需求方面的改进将对生化产品的成本产生显著的积极影响。D " chase1 exe，“INVADERSEXE”# J-BIRD EXE“BS SCO Es”WIN INI p * （ÕSPL167ATMP 5 4 ÕSPL1B2BTMP Z5 ÕSPL1A4BTMP Z5 ÕSPL1406TMP 5”ÕMF0830 TMP \5，+ CTS-9308853伦斯勒理工学院Todd M. Przybycien摘要此SGER项目探索扩展）+yp r +!!F + + (Times New Roman Symbol & Arial " h 4 e M \ 1 Nichelle Coward尼克尔·科沃德

CTS-9308853 Rensselaer Polytechnic Institute Todd M. Przybycien ABSTRACT This SGER project explores the extension of electrochemical chromatography from particulate substrates coated with conducting polymer to monolithic structures. A radial flow unit will be fabricated of very porous reticulated vitreous carbon coated with conducting polymer (e.g. poly-N-alkylpyrrole) and tested for binding capacity and reversible binding of model proteins with different isoelectric points. Improvements of ion exchange chromatography in terms of throughput, separation efficiency and reagent needs will have significant positive effect on the costs of biochemical products. .D " CHASE1 EXE , " INVADERSEXE " # J-BIRD EXE " BS SCO Es " WIN INI p * ( ÕSPL167ATMP 5 4 ÕSPL1B2BTMP Z5 ÕSPL1A4BTMP Z5 ÕSPL1406TMP 5 " ÕMF0830 TMP \5 ,+ CTS-9308853 Rensselaer Polytechnic Institute Todd M. Przybycien ABSTRACT This SGER project explores the extension ) + ı p r + ! ! F + + ( Times New Roman Symbol & Arial " h 4 e M \ 1 Nichelle Coward Nichelle Coward