A Relational Database for Thermodynamic Data on Lipid Mesomorphic Transitions and Miscibility

本奖项的目的是汇编关于脂质热力学特性的数据，以期提供对数据本身和适当文献的随时访问。一个完整的、选择性渗透的膜或膜系统是活细胞的基本特征。细胞膜本质上是一种双分子脂质小叶，在其上有多种蛋白质和其他分子。存在着大量关于脂相行为的信息，其中大部分分散在国内外各种期刊、书籍和论文集的文献中。其目的是将数据汇编成一个单一的、不断修订的关系数据库。这个数据库将被在线访问。数据的磁盘、光盘和硬拷贝将定期发行。该汇编将包括所有已知的合成和生物衍生的脂类在干燥和部分和完全水合状态下的中形和多形相变温度和焓的表。

The objective of this award is to compile data on the thermodynamic characteristics of lipids, with a view to providing ready access to the data itself and to the appropriate literature. An intact, selectively permeable membrane or system of membranes is an essential feature of the living cell. The membrane is in essence a bimolecular lipid leaflet in and on which are situated a variety of proteins and other molecules. There exists a wealth of information on lipid phase behavior much of which is scattered throughout the literature in a variety of journals, books and proceedings both foreign and domestic. The intention is to compile the data in a single, continuously revised relational database. The database will be accessed on- line. Disk, CD-ROM as well as hard copies of the data will be released periodically. The compilation will include a tabulation of all known mesomorphic and polymorphic phase transition temperatures and enthalpies for synthetic and biologically- derived lipids in the dry and in the partially and fully hydrated states.